Trials / Completed
CompletedNCT01626560
The Effects of Daptomycin and Cytokines Production in Comparison With Vancomycin
Effects of Daptomycin in the Levels of IL-1, IL-6 and TNF in Patients With Complicated Cellulitis/Erisipela in Comparison With Vancomycin or Oxacillin
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 20 (actual)
- Sponsor
- Hospital Universitario Evangelico de Curitiba · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Primary: To determine the influence of daptomycin on inflammatory cytokine (IL-1, TNF and IL-6) for the treatment of complicated cellulitis/erysipela compared with alternative treatment (vancomycin or oxacillin). Secondary: To evaluate the clinical outcome of both groups according to levels of the cytokines evaluated.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Daptomycin | daptomycin 4-6mg/kg qd 10 - 14 days |
| DRUG | Vancomycin | Vancomycin 1g q12h 10 - 14 days |
Timeline
- Start date
- 2012-07-01
- Primary completion
- 2015-03-01
- Completion
- 2015-03-01
- First posted
- 2012-06-22
- Last updated
- 2015-03-20
Locations
1 site across 1 country: Brazil
Source: ClinicalTrials.gov record NCT01626560. Inclusion in this directory is not an endorsement.