NCT01626521

Value of Prothrombin Fragment F1+2 in the Diagnosis of Pulmonary Embolism in Patients With Chronic Obstructive Pulmonary Disease (COPD) Exacerbation

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 20 (estimated)
• Sponsor: Hillel Yaffe Medical Center · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To access the clinical usefulness of F1+2 in the diagnosis of PE in patients with AECOPD who require hospitalization. Specifically, to determine whether F1+2 may have an additional value in the subgroup of patients with an abnormal D-dimer,to determine whether it may increase the proportion of patients in whom PE can be safely ruled out and to determine the sensitivity, specificity and NPV of F1+2 at various cut-off values.

Conditions

• Chronic Obstructive Pulmonary Disease
• Pulmonary Embolism

Interventions

Type	Name	Description
OTHER	CT pulmonary angio, blood tests	CT pulmonary angiography to determine PE and laboratory blood tests to determine prothrombin fragments F1+2 in blood of COPD patients

Timeline

• Start date: 2012-07-01
• Primary completion: 2013-01-01
• Completion: 2013-01-01
• First posted: 2012-06-22
• Last updated: 2012-06-22

Locations

1 site across 1 country: Israel