Clinical Trials Directory

Trials / Completed

CompletedNCT01626378

Safety and Efficacy Study Evaluating TRx0237 in Subjects With Behavioral Variant Frontotemporal Dementia (bvFTD)

A Double-Blind, Placebo-Controlled, Randomized, Parallel Group, 12-Month Safety and Efficacy Trial of TRx0237 in Subjects With Behavioral Variant Frontotemporal Dementia (bvFTD)

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
220 (actual)
Sponsor
TauRx Therapeutics Ltd · Industry
Sex
All
Age
79 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to demonstrate the safety and efficacy of TRx0237 in the treatment of patients with behavioral variant frontotemporal dementia (bvFTD).

Conditions

Interventions

TypeNameDescription
DRUGTRx0237TRx0237 100 mg tablet will be administered twice daily.
DRUGPlaceboPlacebo tablets will be administered twice daily. The placebo tablets include 4 mg of TRx0237 as a urinary and fecal colorant to maintain blinding; hence, the placebo group will receive a total of 8 mg/day of TRx0237.

Timeline

Start date
2013-05-01
Primary completion
2016-02-01
Completion
2016-02-01
First posted
2012-06-22
Last updated
2018-03-14

Locations

67 sites across 12 countries: United States, Australia, Canada, Croatia, Germany, Italy, Netherlands, Poland, Romania, Singapore, Spain, United Kingdom

Source: ClinicalTrials.gov record NCT01626378. Inclusion in this directory is not an endorsement.