NCT01622946

The Effect of Topical Application of Tranexamic Acid in Total Hip Arthroplasty Through the Direct Anterior Approach

The Effect of Topical Application of Tranexamic Acid in Total Hip Arthroplasty Through the Direct Anterior Approach. A Prospective, Double Blind, Placebo-controlled Clinical Trial.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Universitaire Ziekenhuizen KU Leuven · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

The effects of topical application of 3g tranexamic acid for 2 hours prior to opening of the suction drain following a total hip replacement

Conditions

• Total Hip Arthroplasty
• Postoperative Blood Loss

Interventions

Type	Name	Description
DRUG	Tranexamic Acid	3g of tranexamic acid is topically applied after THA. The drugs is left for 15 minutes or 2 hours
DRUG	placebo	The patients will receive 3g topical TXA for 15 minutes or 2 hours after THA. 33% of the patients will receive 3g of TXA trough a suction drain for 15 minutes after total hip arthroplasty, then the suction drain is opened. 33% will receive the same amount of TXA but the suction drain will only be opened 2 hours after application. The other patients will receive a placebo in the same manner

Timeline

• Start date: 2012-04-01
• Primary completion: 2020-04-01
• Completion: 2020-04-01
• First posted: 2012-06-19
• Last updated: 2020-11-05

Locations

1 site across 1 country: Belgium