NCT01622881

Analgesic Efficacy of Nefopam in Patients Undergoing Kidney Transplantation

Analgesic Efficacy of Nefopam in Patients Undergoing Kidney Transplantation : Randomized Controlled Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 98 (actual)
• Sponsor: Severance Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 64 Years
• Healthy volunteers: Not accepted

Summary

The investigators examined the efficacy of nefopam in patients undergoing kidney transplantation.

Detailed description

Drug combination are frequently used to relieve postoperative pain. Nefopam can inhibit serotonin, dopamine, and norepinephrine reuptake through central mechanisms. Several studies have demonstrated analgesic efficacy of nefopam in the postoperative period. The purpose of this study is to ascertain the analgesic effect and tolerance of intravenous nefopam in combination with fentanyl based patient-controlled analgesia after kidney transplantation.

Conditions

• Kidney Transplantation

Interventions

Type	Name	Description
DRUG	Normal saline	Normal saline 200mL : the infusion of 4mL/hr for post-operative 48 hours
DRUG	Nefopam	Nefopam 160mg (16 mL) mixed to normal saline 184 mL : the infusion of 4mL/hr for post-operative 48 hours

Timeline

• Start date: 2012-06-01
• Primary completion: 2013-07-01
• Completion: 2013-07-01
• First posted: 2012-06-19
• Last updated: 2013-08-20

Locations

1 site across 1 country: South Korea