NCT01622647

The Effect of Nasal Continuous Positive Airway Pressure (N-CPAP) on Arterial pCO2 During Spinal Anesthesia

The Effect of Nasal Continuous Positive Airway Pressure (N-CPAP) on Arterial pCO2 During Spinal Anesthesia With Intravenous Sedation for Total Knee Arthroplasty

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Pediatrix · Academic / Other
• Sex: All
• Age: 21 Years – 69 Years
• Healthy volunteers: Not accepted

Summary

The proposed study intends to investigate several aspects of the respiratory effects of intravenous sedation of patients undergoing spinal anesthesia for knee replacement surgery. The study will include assessment of PaCO2 during the intraoperative period. PaCO2 is expected to be elevated as a result of intravenous sedation and postural factors. Further, the study will investigate how application of Nasal Continuous Positive Airway Pressure (N-CPAP) may impact PaCO2.

Conditions

• Knee Replacement Surgery

Interventions

Type	Name	Description
OTHER	Nasal Continuous Positive Airway Pressure (NCPAP)	Subjects will receive NCPAP

Timeline

• Start date: 2012-07-01
• Primary completion: 2013-08-01
• Completion: 2013-08-01
• First posted: 2012-06-19
• Last updated: 2013-09-06

Locations

1 site across 1 country: United States