NCT01619176

Acupuncture Study on Rheumatoid Arthritis, Monitoring Microbiome and Blood

Non Inferiority Trial for the Study of Acupuncture on Rheumatoid Arthritis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Chinese Academy of Sciences · Other Government
• Sex: Female
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Acupuncture is used and recommended by the WHO for the treatment of Rheumatoid Arthritis. The molecular bases of this recommendation are not known, the investigators want to compare with the usage of high-throughput molecular technologies the variations occurring in patients treated with acupuncture and conventional treatment with the ones treated with conventional treatment only. The investigators observe the variations in blood and in the gut microbiome.

Conditions

• Rheumatoid Arthritis

Interventions

Type	Name	Description
DRUG	methotrexate	methotrexate: 7.5mg/week to 15mg/week for 3 months
DRUG	non-steroidal anti-inflammatory drug (NSAID)	NSAID: 100mg twice a day for 3 months
DRUG	leflunomide	leflunomide: 20mg/day for 3 months
DRUG	methotrexate	methotrexate: 7.5mg/week to 15mg/week for 3 months
DRUG	non-steroidal anti-inflammatory drug (NSAID)	NSAID: 100mg twice a day for 3 months
DRUG	leflunomide	leflunomide: 20mg/day for 3 months
PROCEDURE	Acupuncture	30 minutes acupuncture every other day for 3 months. Basic acupoints: Zusanli, st36; Taixi，KI3）; Shenxu, BL23 Additional acupoints due to personal condition: Waiguan，SJ5; Baxie，Ex-UE9;Yinlingquan，(SP9）; Quchi，LI11; Yanglingquan，GB34; Xuehai，SP10; Dazhu，BL11; Dazhui，DU14; Pixu，BL20.

Timeline

• Start date: 2012-10-01
• Primary completion: 2014-12-01
• Completion: 2014-12-01
• First posted: 2012-06-14
• Last updated: 2023-11-13
• Results posted: 2023-09-08

Locations

1 site across 1 country: China