NCT01618240

Predictors of the Ability to Protect the Airway in Long-term Ventilated Patients

Determining Predictors of Adequate Upper Airway Function in Long-term Ventilated Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 30 (actual)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

First part of a 2 part study with the same IRB protocol #, and labeled 'A'. Investigators hypothesized that clinical muscle strength assessment (manual muscle testing) predicts the ability to protect the airway during swallowing in long-term ventilated subjects. More specifically, the investigators hypothesized that low muscle strength is associated with the inability to clear secretions from the peri-laryngeal area (valleculae and pyriform sinus residue scale (VPSR scale \[NRS: 0-4\] of \> 1) and entering the materials into airway (PAS scale \[1-8\]\> 1), which should predispose to endotracheal aspiration.

Conditions

• Swallowing Disorder
• Aspiration
• Long Term Ventilation

Interventions

Type	Name	Description
OTHER	Muscle Strength Measurement	MRC score (0-60) is a clinical assessment of muscle power on abduction of the arm, flexion of the forearm, extension of the wrist, flexion of the leg, extension of the knee and dorsal flexion of the foot with the score of (0-5) on each measurement
OTHER	Ventilator	A mechanical ventilator is used to assist or replace spontaneous breathing.

Timeline

• Start date: 2011-01-01
• Primary completion: 2012-04-01
• Completion: 2012-04-01
• First posted: 2012-06-13
• Last updated: 2014-10-13
• Results posted: 2013-08-27

Locations

1 site across 1 country: United States