NCT01616498

Lean Muscle Function

Obesity and Muscle Function Pilot Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 24 (actual)
• Sponsor: Wake Forest University · Academic / Other
• Sex: All
• Age: 65 Years – 75 Years
• Healthy volunteers: Accepted

Summary

This pilot study is designed to determine the relationship between intra-myocellular lipids and muscle contractility in fibers from obese and non-obese older adults. Obese participants are being recruited for an on-going weight loss intervention study and this application seeks approval to recruit and enroll a lean comparison group of non-obese older adults. The primary goal of this study is to characterize the contractile properties of single muscle fibers and whole muscle in healthy, non-obese individuals under the same recording conditions the investigators used for the obese population to begin to determine whether fat infiltration accounts for diminished force.

Conditions

• Single Muscle Fibers

Timeline

• Start date: 2012-06-01
• Primary completion: 2013-09-01
• Completion: 2013-11-01
• First posted: 2012-06-11
• Last updated: 2017-03-14

Locations

1 site across 1 country: United States