NCT01616407

Effects of MDMA and Methylphenidate on Social Cognition

Effects of MDMA (Ecstasy) and Methylphenidate (Ritalin) on Social Cognition

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: University Hospital, Basel, Switzerland · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to assess and compare the effects of a single dose of 3,4-methylenedioxymethamphetamine (MDMA)and methylphenidate (MPH) on emotional and social cognition in healthy subjects. The investigators hypothesize that MDMA enhances affective perception for positive and impairs perception for negative emotional stimuli compared to placebo or MPH.

Conditions

• Social Cognition

Interventions

Type	Name	Description
DRUG	3,4-Methylenedioxymethamphetamine	75 mg per os, single dose
DRUG	Methylphenidate	40 mg per os, single dose
DRUG	Placebo	capsules identical to MDMA or methylphenidate but containing no active drug

Timeline

• Start date: 2012-08-01
• Primary completion: 2012-12-01
• Completion: 2013-04-01
• First posted: 2012-06-11
• Last updated: 2018-12-11

Locations

1 site across 1 country: Switzerland