NCT01614158

Assessment of Visual Field-related Endpoints in Patients With Non-arteritic Ischemic Optic Neuropathy

Pilot SINN; Assessment of Visual Field (vf)-Related Endpoints in Patients With Non-arteritic Ischemic Optic Neuropathy (N-AION)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 16 (actual)
• Sponsor: University Hospital Tuebingen · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This present research project intends to collect five quantitative test series: * perimetric examination using static stimuli, assessing the entire (80 degree) visual field with a fast thresholding algorithm (GATE) \[Schiefer 2008\] to know the extent/ magnitude of the visual field defect and its variability within the cohort and over time * D-BCVA, using FrACT \[Bach 2007\] and EDTRS chart \[Ferris 1982\] * RAPD (using swinging flashlight test). * IOP (using applanation tonometer) * RNFT and RNFV using Spectralis OCT (star scan, ring scan 2,8 mm, and volume scan) Optic disk morphology will be documented by fundus photography. This assessment of the above-mentioned data is needed in order to allow for estimation of the spontaneous course / fluctuation of the (quantified) functional and morphometric parameters of the N-AION patients during the follow-up period. This is essential for the estimation of the sample size of the subsequently intended SINN study, that is intended to compare different therapeutic strategies in N-AION patients.

Conditions

• Non-arteritic Ischemic Optic Neuropathy

Interventions

Type	Name	Description
DEVICE	perimetry	perimetric examination using static stimuli, assessing the entire (80 degree) visual field with a fast thresholding algorithm (GATE) \[Schiefer 2008\] to know the extent/ magnitude of the visual field defect and its variability within the cohort and over time
OTHER	D-BCVA	D-BCVA using EDTRS chart
OTHER	RAPD	RAPD using swinging flashlight test
DEVICE	IOP	IOP using applanation tonometer
DEVICE	Spectralis OCT	RNFT and RNFV using Spectralis OCT (star scan, ring scan 2,8 mm and volume scan)
OTHER	Fundus photography	Optic disk morphology will be documented by fundus photography

Timeline

• Start date: 2009-04-01
• Primary completion: 2011-02-01
• Completion: 2011-02-01
• First posted: 2012-06-07
• Last updated: 2014-05-28

Locations

1 site across 1 country: Germany