NCT01613612

Implantation of Bone Marrow Cells to Treat Avascular Necrosis of Femoral Head (ANFH)

Control Study of Implantation of Enriched Bone Marrow Cells for the Treatment of Avascular Necrosis of Femoral Head

• Status: Unknown
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Guangdong Provincial People's Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare the efficacy of autologous enriched bone marrow cell implantation combined with core decompression to single core decompression for the treatment of avascular necrosis of femoral head.

Conditions

• Avascular Necrosis of Femur Head

Interventions

Type	Name	Description
PROCEDURE	core decompression	minimal surgical invention to drill a core to the femoral head to release pressure
PROCEDURE	Enriched BMCs implantation combined with core decompression	Patients are subjected to bone marrow aspiration from the anterior iliac crest. Mononuclear cells are enriched from patients' bone marrow by centrifuge, which are grafted with autologous cortical bone and implanted to the necrotic zone of the femoral head.

Timeline

• Start date: 2009-03-01
• Primary completion: 2012-08-01
• Completion: 2012-12-01
• First posted: 2012-06-07
• Last updated: 2012-08-14