NCT01613547

The Effect of Routine Antibiotic Use in the Outpatient Treatment of Severely Malnourished Children Without Complications

The Effect of Routine Antibiotic Use in the Outpatient Treatment of Severely Malnourished Children Without Complications: Maradi, Niger

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 2,412 (estimated)
• Sponsor: Epicentre · Academic / Other
• Sex: All
• Age: 6 Months – 59 Months
• Healthy volunteers: Not accepted

Summary

This study will be conducted as a randomized, double-blind, placebo-controlled trial to compare routine antibiotic prescription vs. no routine antibiotic prescription in the management of uncomplicated cases of severe acute malnutrition treated in the community in terms of nutritional recovery. The investigators hypothesize that there will be no significant difference in terms of the risk of nutritional recovery among children uncomplicated cases of severe acute malnutrition treated in the community that receive routine antibiotic prescription and those who receive no routine antibiotic prescription.

Conditions

• Severe Acute Malnutrition

Interventions

Type	Name	Description
DRUG	Amoxicillin	80 mg/kg/day for 7 days
DRUG	Placebo	7 days

Timeline

• Start date: 2012-10-01
• Primary completion: 2014-03-01
• Completion: 2014-05-01
• First posted: 2012-06-07
• Last updated: 2014-05-21

Locations

1 site across 1 country: Niger