NCT01612130

Valerian for Conscious Sedation in Patients Submitted to Impacted Lower Third Molars Surgery

Valeriana Officinalis L. for Conscious Sedation in Patients Submitted to Impacted Lower Third Molars Surgery: A Randomized, Double-Blind, Placebo-Controlled Crossover Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Federal University of the Valleys of Jequitinhonha and Mucuri · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

The aim of the present study was to evaluate the efficacy of Valeriana officinalis L. 100 mg in single oral doses one hour preoperative as conscious sedation during the impacted lower third molar surgery.

Detailed description

Evaluate the efficacy of Valeriana officinalis L. (Valerian) for control of anxiety during third molar surgery. Study design: A single oral dose of either valerian (100 mg) or placebo was randomly administered one hour before each surgical procedure to 20 volunteers between 17 and 31 years of age. Anxiety level was assessed through questionnaires, physiological parameters (blood pressure and heart rate) and the observation of signs.

Conditions

• Dental Anxiety
• Blood Pressure
• Heart Rate

Interventions

Type	Name	Description
DRUG	100 mg of Valeriana officinalis L	A single dose of 100 mg of Valeriana officinalis L., 1 hour prior to surgical procedures
DRUG	Placebo 100mg	A single dose of 100 mg of placebo orally, 1 hour prior to surgical procedures

Timeline

• Start date: 2003-03-01
• Primary completion: 2003-08-01
• Completion: 2003-08-01
• First posted: 2012-06-05
• Last updated: 2012-06-06

Locations

1 site across 1 country: Brazil