NCT01609725

Periodontal Therapy in Coronary Artery Patients

Impact of Periodontal Therapy in Flow-mediated Dilation and Serum Levels of Cardiovascular Risk Biomarkers in Coronary Artery Disease Patients: 12 Months Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 93 (actual)
• Sponsor: Federal University of Rio Grande do Sul · Academic / Other
• Sex: All
• Age: 35 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Gingival inflammation has been associated with cardiovascular diseases, including heart attack and stroke, because of elevation of blood risk markers such as cholesterol, glucose and C reactive protein. The treatment of gingival diseases decreases the concentration of these risk factors in the blood of cardiovascular patients.

Conditions

• Cardiovascular Diseases
• Atheroma
• Coronary Artery Disease

Interventions

Type	Name	Description
DEVICE	Subgingival scaling and root planing	Oral hygiene instruction and motivation will be provided altogether with scaling and root planing of all teeth affected by periodontitis under local anesthesia
DEVICE	Oral prophylaxis	One session of supraginigval calculus removal

Timeline

• Start date: 2012-01-01
• Primary completion: 2016-07-01
• Completion: 2017-12-01
• First posted: 2012-06-01
• Last updated: 2019-10-01

Locations

1 site across 1 country: Brazil