NCT01606592

Psychotherapy Outcome and Self-selection Effects in Panic Disorder

Phase 2/3 Study of Panic Control Treatment vs Panic-Focussed Psychodynamic Psychotherapy Under Randomized and Self-Selection Conditions

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 216 (actual)
• Sponsor: Region Skane · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The efficacy of two forms of psychotherapy with panic disordered patients, a cognitive-behavioral and a psychodynamic one, are compared under two different, randomized conditions: randomization or self-selection. The basic hypotheses are that the efficacy of both treatments is higher and that the efficacy difference is smaller under self-selection than randomized conditions.

Detailed description

After thorough assessment persons with a panic disorder diagnosis are randomly assigned to three arms: one randomization, one self-selection, and one a low-contact waiting list one. In the randomization arm (R) 95 persons are randomly assigned to Panic Control Treatment (PCT) or Panic-Focused Psychodynamic Psychotherapy (PFPP); in the self-selection arm (SS) 95 persons are offered, after adequate information, to choose which of the two they prefer. Twenty-six persons are initially randomized to a three-month waiting list (with sparse contact over telephone), after which they will be re-randomized, either to further randomization (to PCT or PFPP) or to self-selection. The four groups (R/PCT; R/PFPP; SS/PCT; SS/PFPP) will be compared on the basis of intake and repeated outcome/follow-up assessment.

Conditions

• Panic Disorder (With or Without Agoraphobia)

Interventions

Type	Name	Description
BEHAVIORAL	Panic Control Treatment (PCT)	Manualized, 13 sessions (60 min, sometimes extended to 90-120) completed in 12-16 weeks. Total duration 840-1080 min.
BEHAVIORAL	Panic-Focused Psychodynamic Psychotherapy (PFPP)	Manualized, 19-24 sessions (45 min) completed in 12-16 weeks. Total duration 855-1080 min.
OTHER	Waiting-list	Sparse telephone contact during 12 weeks, then re-randomization

Timeline

• Start date: 2010-01-01
• Primary completion: 2019-06-01
• Completion: 2021-02-01
• First posted: 2012-05-25
• Last updated: 2021-03-12

Locations

1 site across 1 country: Sweden