NCT01595672

Early High-volume Continuous Veno-venous Hemofiltration for Patients With Severe Acute Pancreatitis

Early High-volume Continuous Veno-venous Hemofiltration for Patients With Severe Acute Pancreatitis: Single-center, Randomized, Controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 56 (estimated)
• Sponsor: Air Force Military Medical University, China · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine the effect and safety of early high-volume continuous veno-venous hemofiltration for patients with severe acute pancreatitis.

Detailed description

The investigators anticipated that early high-volume continuous veno-venous hemofiltration (EHVCVVH) would result in a decrease of the composite of persistent organ failure or death by eliminating inflammatory mediators in blood. This study is designed to evaluate the impact of EHVCVVH on patients with severe acute pancreatitis.

Conditions

• Acute Pancreatitis

Interventions

Type	Name	Description
DEVICE	AN69 hemofilter	An AN69 hemofilter (1.6 m2 surface area, 35-KD limit; Baxter Healthcare Corp. Deerfield, IL, USA) will be used for EHCVVH.
OTHER	conventional treatments	Patients receive conventional treatments recommended by guidelines only.

Timeline

• Start date: 2012-04-01
• Primary completion: 2013-02-01
• Completion: 2013-03-01
• First posted: 2012-05-10
• Last updated: 2012-05-10

Locations

1 site across 1 country: China