NCT01594021

Efficacy of Preemptive Volume Loading to Prevent Arterial Hypotension During Induction of General Anesthesia

• Status: Terminated
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 17 (actual)
• Sponsor: Hopital Foch · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Induction of general anesthesia induces frequently arterial hypotension. The short term goal of this study is to evaluate if preemptive volume loading prevents such complication.

Detailed description

This is a randomized, prospective study which will include a total of 200 patients who are scheduled to undergo elective surgery. The research participants will be randomly assigned to * a control group that will receive a low preemptive volume loading (50 mL of gelatin), * a protocol group that will receive a high preemptive volume loading (500 mL of gelatin). Volume loading is preceded by the measurement of stroke volume and cardiac output before and after a passive leg elevation test and followed by a standardized anesthetic protocol.

Conditions

• Anesthesia

Interventions

Type	Name	Description
DRUG	Gelatin 500 mL	intravenous administration
DRUG	Gelatin 50 mL	intravenous administration

Timeline

• Start date: 2012-07-01
• Primary completion: 2014-06-01
• Completion: 2014-06-01
• First posted: 2012-05-08
• Last updated: 2016-10-31

Locations

1 site across 1 country: France