NCT01593631

Acid Lactase in Combination With Yoghurt Bacteria for Improvement of Lactose Digestion in Lactose Malabsorbers

A Combination of Yoghurt Bacteria and Acid Lactase From Aspergillus Oryzae Improves Lactose Digestion in Lactose Malabsorbers More Reliably Than Preparations Containing Acid Lactase or Yoghurt Bacteria Alone

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Vitacare Gmbh & Co. KG · Industry
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Fermented dairy products, especially real Yoghurt, are often tolerated better by lactose malabsorbers than unfermented dairy products. The intake of dietary supplements containing acid Lactase derived from Aspergillus oryzae with lactose containing foodstuffs is known to reduce/alleviate symptoms of lactose intolerance in lactose malabsorbers. The study aims to compare the effect of the intake of a combination of yoghurt bacteria and acid lactase to the effect of yogurt bacteria or acid lactase alone on the lactose digestion in lactose malabsorbers. It is hypothized that the combination preparation will be more effective and/or will show a more reliable effect than the two mono-preparations.

Conditions

• Lactose Malabsorption

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Acid lactase	capsules cotaining 3300 FCC units of acid lactase
DIETARY_SUPPLEMENT	Acid lactase	capsules containing 9000 FCC of acid lactase
DIETARY_SUPPLEMENT	Lyoph. yoghurt bacteria	capsules containing 2 billion lyoph. yoghurt bacteria
DIETARY_SUPPLEMENT	Acid lactase plus yoghurt bacteria	Capsules containing 3300 FCC of acid lactase and 2 billion lyoph. yoghurt bacteria
DIETARY_SUPPLEMENT	Placebo	Capsules containing di-calcium-phosphate

Timeline

• Start date: 2009-09-01
• Primary completion: 2010-04-01
• Completion: 2010-04-01
• First posted: 2012-05-08
• Last updated: 2012-05-08

Locations

1 site across 1 country: Germany