NCT01588925

Hearing Preservation Using Dexamethasone and Hyaluronic Acid for Cochlear Implantation

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 18 (actual)
• Sponsor: University of Sao Paulo General Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The objective of the present study is to investigate the effect dexamethasone and hyaluronic acid have on hearing preservation

Detailed description

Many efforts have been made to prevent residual hearing loss after cochlear implantation, such as the development of soft surgical techniques and pharmacological protection. In this study we investigate whether the topical application of dexamethasone and hyaluronic acid prevents residual hearing loss.

Conditions

• Hearing Loss

Interventions

Type	Name	Description
DEVICE	Cochlear Implantation	Cochlear implantation using Hybrid L24 Implant
DRUG	Cochlear Implantation+dexamethasone	Cochlear implantation using Hybrid L24 Implant,dexamethasone (4mg/ml) in the round window
DRUG	Cochlear Implantation+dexamethasone+hyaluronic acid	Cochlear implantation using Hybrid L24 Implant,dexamethasone (4mg/ml) in the round window and hyaluronic acid (10mg/ml) in the electrode array

Timeline

• Start date: 2011-11-01
• Primary completion: 2013-02-01
• Completion: 2014-01-01
• First posted: 2012-05-01
• Last updated: 2014-10-03

Locations

1 site across 1 country: Brazil