NCT01588834

Histology of Functional Density in Premenopausal Breast

Pilot Study to Examine Histological Characteristics of Mammographic Density With Molecular Breast Imaging: Part 2 - Premenopausal Women

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 23 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: Female
• Age: 40 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The investigators hypothesize that knowledge of the functional behavior of areas of mammographic density will enable more specific identification of dense tissue at-risk for breast cancer, ultimately providing predictive information on an individual's risk of developing breast cancer.

Detailed description

The specific aims are: * In women with increased mammographic density (MD), determine the histological characteristics of functionally dense tissue compared to that of non-functionally dense tissue via core-needle biopsy of the breast. * In women with increased mammographic density (MD), determine the correlations between the total percent area of functional density (FD) on MBI, percent density of MD on mammogram, and histological characteristics of dense tissue

Conditions

• Dense Breasts
• Breast Cancer

Interventions

Type	Name	Description
PROCEDURE	breast biopsy	ultrasound-guided core needle biopsy of healthy, mammographically dense breast tissue

Timeline

• Start date: 2012-04-01
• Primary completion: 2016-02-01
• Completion: 2016-02-01
• First posted: 2012-05-01
• Last updated: 2016-05-20

Locations

1 site across 1 country: United States