NCT01584999

Effects on Septic Patient's Microcirculation of the Transfusion of Different Types of Concentrated RBCs.

Effects on the Septic Patient's Microcirculation of the Transfusion of Three Different Types of Concentrated Red Blood Cells.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Università Politecnica delle Marche · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Aim of the study is to evaluate the effects, on microcirculation of septic patient, of three types of RBCs: 1- fresh standard RBCs (storage \<10 days); 2-leukodepleted RBCs and 3-old standard RBCs (storage \>15 days) respectively. Before and 1 hour after the transfusion, microcirculation is evaluated using Sidestream Dark Field Imaging (SDF) and Near InfraRed Spectroscopy (NIRS) with vascular occlusion test. We also monitor temperature, heart rate, mean blood pressure, hemochrome, blood gases, blood lactates and SOFA score.

Conditions

• Septic Patients

Interventions

Type	Name	Description
BIOLOGICAL	Blood transfusion	RBCs have been transfused in septic patient admitted in ICU

Timeline

• Start date: 2011-02-01
• Primary completion: 2012-02-01
• First posted: 2012-04-25
• Last updated: 2012-05-23

Locations

1 site across 1 country: Italy