NCT01582958

The Effect of OMT on Patients With COPD: Correlating Pulmonary Function Tests With Biochemical Alterations

The Effect of Osteopathic Manipulative Treatment on Patients With Chronic Obstructive Pulmonary Disease:Correlating Pulmonary Function Tests With Biochemical Alterations

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 45 (actual)
• Sponsor: Michigan State University · Academic / Other
• Sex: All
• Age: 49 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This project proposes to test the hypothesis that osteopathic manipulative treatment (OMT) given to patients with moderate to severe chronic obstructive pulmonary disease (COPD) enrolled in a 12-week pulmonary rehabilitation program (PRP) will result in improved respiratory pump function over and above that seen in sham and control groups. Specifically, we will study the effects of three OMT techniques: (a) thoracic inlet indirect myofascial release; (b) rib raising with continued stretch of the paraspinal muscle to the L2 level; and (c) cervical paraspinal muscle stretch with suboccipital muscle release. The key clinical readouts will include: spirometry, P100 (and index of diaphragm and inspiratory muscle efficiency), maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP), as well as laser evaluation of chest wall excursion. Supplementing these objective parameters will be several more subjective clinical outcome measures: exercise tolerance (6-minute walk test), dyspnea (shortness of breath questionnaire), and quality of life questionnaire. Finally, an attempt will be made to correlate biochemical alterations that may shed light on the biological mechanism underlying the OMT procedures.

Detailed description

According to the above directions (provide a more extensice description, if desired), I am choosing to just submit the brief summary. Thank you, Sherman Gorbis, DO

Conditions

• Chronic Obstructive Pulmonary Disease

Interventions

Type	Name	Description
PROCEDURE	Osteopathic Manipulative Treatment (OMT)	Osteopathic Manipulative Treatment (OMT) is the therapeutic application of manually guided forces by an Osteopathic physician to improve physiologic function.
OTHER	sham omt	Hands are placed on subjects the same as omt arm but no omt is provided.

Timeline

• Start date: 2013-04-01
• Primary completion: 2015-08-01
• Completion: 2015-08-01
• First posted: 2012-04-23
• Last updated: 2015-10-08

Locations

1 site across 1 country: United States