NCT01582542

Desmopressin for Improving Nocturnal Enuresis in Patients After Radical Cystectomy With Bladder Reconstruction

Usage of Desmopressin fo Improving Nocturnal Enuresis in Patients After Radical Cystectomy With Orthotopic Bladder Reconstruction

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Rabin Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to prospectively assess whether Desmopressin, given for a period of month to patients after radical cystectomy with orthotopic bladder reconstruction, improves and lowers the rate of nocturnal enuresis.

Detailed description

We will prospectively assess the utilization of Desmopressin in improving nocturnal enuresis in patients after radical cystectomy with orthotopic bladder reconstruction. Patients after radical cystectomy with neobladder reconstruction will be given Desmopressin 0.1 mg once a day for a duration of one month. Before beginning treatment patients will be given the NNES-Q questionnaire to assess severity of nocturnal enuresis. At the end of treatment, the same questionnaire will be given to all patients to assess if nocturnal enuresis improved. Sodium levels will be tested before treatment, 2 weeks after beginning treatment and at the end of treatment.

Conditions

• Nocturnal Enuresis

Interventions

Type	Name	Description
DRUG	Desmopressin	Patients after radical cystectomy with orthotopic bladder reconstruction that suffer from night time urinary incontinence will be enrolled in the study. They will be given for a period of one month after informed consent, Desmopressin At a dosage of 0.1 M"G per day. The rate of improvement of night time urinary incontinence will be measured.

Timeline

• Start date: 2012-04-01
• Primary completion: 2013-12-01
• Completion: 2014-03-01
• First posted: 2012-04-20
• Last updated: 2012-04-20

Locations

1 site across 1 country: Israel