Clinical Trials Directory

Trials / Completed

CompletedNCT01575665

Normalizing CO2 in Chronic Hyperventilation by a Novel Breathing Mask: A Pilot Study

CO2 Rebreathing by a Partial Rebreathing Mask as a Treatment of Chronic Idiopathic Hyperventilation - a Pilot Study

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
6 (actual)
Sponsor
University of Aarhus · Academic / Other
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

Background: Chronic Idiopathic Hyperventilation (CIH) is a form of dysfunctional breathing which has proven hard to treat effectively. The investigators hypothesised that by periodically inducing normocapnia over several weeks, it would be possible to raise the normal resting level/set point of CO2 and achieve a reduction of symptoms. Methods: Six CIH patients were treated two hours a day for four weeks with a novel breathing mask. The mask was used to induce normocapnia in these chronically hypocapnic patients. Capillary blood gases (PcCO2, pH, Standard Base Excess (SBE) etc.) were measured at baseline and once each week at least three hours after mask use, as well as spirometric values, breath holding tolerance and hyperventilation symptoms as per the Nijmegen Questionnaire (NQ),.

Conditions

Interventions

TypeNameDescription
DEVICEPartial Rebreathing MaskInducing normal CO2 for two hours a day for four weeks

Timeline

Start date
2011-02-01
Primary completion
2011-06-01
Completion
2011-06-01
First posted
2012-04-11
Last updated
2016-05-19

Locations

1 site across 1 country: Denmark

Source: ClinicalTrials.gov record NCT01575665. Inclusion in this directory is not an endorsement.