Clinical Trials Directory

Trials / Completed

CompletedNCT01573572

Extension Study to Gather Data on Effect of Macugen on the Corneal Endothelium

A Phase IV, Open Label, Multi-center Study to Assess the Effect of Intravitreal Injections of Macugen (Pegaptanib Sodium Injection) Administered Every 6 Weeks for 48 Weeks on the Corneal Endothelium.

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
131 (actual)
Sponsor
Bausch & Lomb Incorporated · Industry
Sex
All
Age
50 Years
Healthy volunteers
Not accepted

Summary

This study was conducted because the FDA requested clinical information on potential effects of intravitreal injections of Macugen (pegaptanib sodium injection) on the corneal endothelium from a 1-year (minimum) post-approval clinical study to support that there are no adverse effects on the corneal endothelium following intravitreal injections of Macugen.

Conditions

Interventions

TypeNameDescription
DRUGpegaptanib sodium injection0.3mg of Macugen in a single-use, prefilled glass syringe given every 6 weeks for 48 weeks

Timeline

Start date
2010-04-22
Primary completion
2019-11-14
Completion
2019-11-14
First posted
2012-04-09
Last updated
2021-01-08
Results posted
2020-10-14

Locations

4 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT01573572. Inclusion in this directory is not an endorsement.