Trials / Completed
CompletedNCT01572831
PCT and Clinical Algorithm for Determination of Duration of Antibiotics
A Pilot Study to Evaluate a Procalcitonin-Based Algorithm for Duration of Antibiotic Therapy in Critically Ill Patients
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 1 (actual)
- Sponsor
- Fraser Health · Academic / Other
- Sex
- All
- Age
- 19 Years
- Healthy volunteers
- Not accepted
Summary
Patients in the ICU whose infection is resolving will be randomized to standard duration of antibiotics compared to duration determined by a combination of a procalcitonin value and a simple evaluation of clinical status.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | PCT and clinical algorithm for stopping abx | In the experimental arm, antibiotics will be stopped based upon the PCT-guided algorithm. This PCT algorithm also incorporates clinical parameters to ensure utmost safety for the patients. These clinical parameters are; resolution of fever (temperature less than 38.3 and greater than 36.0), shock (on no vasopressors), and leukocytosis (\<12,000 and \>4,000). |
Timeline
- Start date
- 2012-05-01
- Primary completion
- 2013-09-01
- Completion
- 2013-09-01
- First posted
- 2012-04-06
- Last updated
- 2015-05-25
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT01572831. Inclusion in this directory is not an endorsement.