NCT01572337

Early Non-invasive Ventilation Outside the Intensive Care Unit

Reducing the Need for Intensive Care Unit in Hospitalized Patients With Early Respiratory Failure Using the Non-invasive Ventilation Technique. A Multicentre Randomized Study.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 520 (actual)
• Sponsor: Università Vita-Salute San Raffaele · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

A large multicentre, randomized, controlled trial to demonstrate that non invasive ventilation given at an early stage of acute respiratory failure (ARF) outside the intensive care unit (ICU) can prevent the deterioration of ARF and the need for ICU when compared to the best available treatment usually performed in the non-ICU wards.

Conditions

• Early Acute Respiratory Failure

Interventions

Type	Name	Description
PROCEDURE	Non-invasive ventilation	Early non-invasive ventilation will be given to patients at an early stage of acute respiratory failure
OTHER	Standard care

Timeline

• Start date: 2012-04-01
• Primary completion: 2023-08-17
• Completion: 2024-07-18
• First posted: 2012-04-06
• Last updated: 2025-08-07

Locations

14 sites across 3 countries: Greece, Italy, Kazakhstan