NCT01569945

Hormonal Stimulation in IUI Treatment: Is Clomifen Combined With Ethinyl Estradiol Better, Worse or Equal to Menopur

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 371 (actual)
• Sponsor: University Hospital, Gasthuisberg · Academic / Other
• Sex: Female
• Age: 18 Years – 42 Years
• Healthy volunteers: Accepted

Summary

What is the best medication for hormonal stimulation in cycles with high intra-uterine insemination: tablets of Clomifen (5 days) followed by tablets of Ethinyl Estradiol (5 days) or daily injections with Human Menopausal Gonadotropin (Menopur)?

Conditions

• Subfertility

Interventions

Type	Name	Description
DRUG	Clomifen, Ethinyl Estradiol	starting on day 2 or 3 of the cycle: 1 tablet of Clomifen each day, for 5 days in a row. Dose 50mg or in subsequent cycles, 25 mg or 100 mg or 150 mg. After the 5 days of Clomifen, one tablet of Ethinyl Estradiol 50 mg per day, for 5 days in a row or until beta hCG is injected
DRUG	Menotropins	Starting on day 2 or 3 of the cycle, a daily subcutaneous injection of 37.5 IU or 75.0 IU

Timeline

• Start date: 2004-09-01
• Primary completion: 2010-12-01
• Completion: 2011-12-01
• First posted: 2012-04-03
• Last updated: 2014-09-10

Locations

1 site across 1 country: Belgium