NCT01567787

Proton Radiation Therapy for Spinal Tumors

Spinal Tumor Proton Protocol

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University of Florida · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine if Proton Therapy can provide effective and safe treatment for Malignant Peripheral Nerve Sheath Tumors of the spine and Neurofibromas of the spine.

Detailed description

Proton therapy may provide the benefits of local control or palliation, while reducing the risk associated with photon radiation, by delivering therapeutic doses to a well-defined target area with significant reduction in the integral dose. A dosimetry comparison of protons and photons at the University of Florida Proton Therapy Institute confirmed the feasibility of proton irradiation of these tumors with less exposure of normal tissue to radiation than expected with photon techniques. This reduced radiation exposure to uninvolved normal tissues is expected to decrease the risk of radiation-induced second malignancies and neoplasms.

Conditions

• Nerve Sheath Tumors
• Neurofibroma

Interventions

Type	Name	Description
RADIATION	Proton Radiation for MPNST	30 CGE at 6 CGE/Fx
RADIATION	Proton Radiation for neurofibromas	25 CGE at 5 CGE/Fx

Timeline

• Start date: 2013-06-01
• Primary completion: 2015-08-01
• Completion: 2015-08-01
• First posted: 2012-03-30
• Last updated: 2017-02-10