NCT01565057

Gastric Layering Study

A Study on the Effect of Gastric Layering and Emptying Induced by a Food Emulsion

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Quadram Institute Bioscience · Academic / Other
• Sex: Male
• Age: 20 Years – 50 Years
• Healthy volunteers: Accepted

Summary

This comparative study is designed to compare the gastric layering and rates of emptying and by inference rates of digestion of two food emulsions. Two types of dairy based foods will be used, one which will sediment in the stomach and one that will not. On each of two study days, a total of 9 post drink MRI scans will be taken to assess gastric layering and emptying. Cannulation will allow blood samples to be taken periodically for subsequent analysis for the presence of specific digestion related hormones. A total volume of 36 ml of blood will be removed and volunteers will also be asked to complete a questionnaire at predetermined times to assess feelings of satiation.

Conditions

• Healthy Volunteers

Interventions

Type	Name	Description
OTHER	sedimenting meal	The active system quickly forms a sedimenting layer of small particles that contain most of the caloric content of the system. This system is made by adding finely grated cheese (particle size 0.5-2 mm) to yoghurt and consumption is followed by drinking 327 ml water.

Timeline

• Start date: 2011-08-01
• Primary completion: 2012-04-01
• Completion: 2012-05-01
• First posted: 2012-03-28
• Last updated: 2012-05-07

Locations

1 site across 1 country: United Kingdom