NCT01564979

Effect on Tear Functions of Pretarsal and Preseptal Techniques of Botulinum Toxin Type A Injection in Hemifacial Spasm

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 26 (estimated)
• Sponsor: Khon Kaen University · Academic / Other
• Sex: All
• Age: 20 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether pretarsal and preseptal techniques of Botulinum toxin type A injection have any effect on tear functions.

Detailed description

Botulinum toxin type A has been used for hemifacial spasm since 1986. of Botulinum toxin type A can be subcutaneously injected at pretarsal or preseptal portion of orbicularis muscle. Blepharoptosis has been reported less frequently with pretarsal technique, however dry eye was noticed in one patient treated with pretarsal botulinum toxin type A for cosmetic purpose.

Conditions

• Hemifacial Spasm

Interventions

Type	Name	Description
DRUG	preseptal injection of botulinum toxin type A	botulinum toxin type A (Botox)2.5 units, 5 points
DRUG	pretarsal injection of Botulinum toxin type A	Botulinum toxin type A 2,5 units, 5 points

Timeline

• Start date: 2012-04-01
• Primary completion: 2012-09-01
• Completion: 2012-12-01
• First posted: 2012-03-28
• Last updated: 2012-03-28

Locations

1 site across 1 country: Thailand