NCT01560611

A New Non-invasive Marker to Detect Silent Hypoxia in Patients Undergoing Cardiac Surgery

The Somatic-to-cerebral Oxygen Saturation Gradient as a Non-invasive Index of Anaerobic Threshold in High-risk Cardiac Surgical Patient

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 60 (estimated)
• Sponsor: University Hospital, Strasbourg, France · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In patients undergoing cardiac surgery under cardiopulmonary bypass, some organs like brain and heart are preserved while others (skin, gut and skeletal muscle) are being underperfused. This phenomenon is related to silent peripheral vasoconstriction that is not clinically available but threatens end-organ perfusion and carries the risk of multi-organ failure. By measuring non-invasively the somatic-to-cerebral oxygen saturation gradient, the present study aims at detecting silent peroperative hypoperfusion episodes. The investigators hypothesize that gradient, measured during the surgical procedure, will predict the occurrence of anaerobic metabolism, ascertained by an elevation of blood lactate concentration, measured in intensive care unit.

Conditions

• Cardiac Surgical Procedures
• High-risk Surgical Patient
• Anaerobic Threshold

Interventions

Type	Name	Description
DEVICE	Near infrared spectroscopy

Timeline

• Start date: 2012-03-01
• First posted: 2012-03-22
• Last updated: 2012-03-22

Locations

1 site across 1 country: France