Trials / Completed
CompletedNCT01557855
Investigation of a Novel Gene Expression Test (ASGES or Corus CAD) for Diagnosis of Obstructive Coronary Artery Disease
Enhanced Assessment of Chest Pain and Related Symptoms in the Primary Care Setting Through the Use of a Novel Personalized Medicine Genomic Test: Results From a Prospective Registry Study.
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 342 (actual)
- Sponsor
- CardioDx · Industry
- Sex
- All
- Age
- 21 Years
- Healthy volunteers
- Not accepted
Summary
The objective of this study is to collect data on the commercial use of Corus CAD (Age/Sex/Gene Expression score - ASGES) blood test to evaluate the clinical referral patterns of Primary Care Physicians after receipt of their patients' Corus Score, and to better understand patient management patterns for clinicians ordering the test.
Detailed description
This is a prospective, multicenter observational registry collecting and analyzing commercial utilization data of the Corus CAD assay ("Test") also known as Age/Sex/Gene Expression score (ASGES) . The study will prospectively enroll approximately 670 evaluable subjects from qualified sites and evaluate the rate of referral versus Corus CAD (ASGES) score as continuous variables. Objective of the study is to assess whether the score provided by the Corus CAD (Age/Sex/Gene Expression score - ASGES) test has an effect on the Primary Care Physician's patient management and referral patterns once received: 1. No further cardiac testing or treatment 2. Medical therapy for angina or non-cardiac chest pain 3. Referral to a cardiologist for stress testing with or without imaging, CT angiography, or invasive cardiac catheterization. Since it takes approximately two days for the physician to receive the result of the Corus CAD (Age/Sex/Gene Expression score - ASGES) , initial diagnostic testing will reflect local standard of care.
Conditions
- Coronary Artery Disease
- Angina Pectoris
- Chest Pain
- Cardiovascular Diseases
- Coronary Heart Disease
- CAD
- CVD
- CHD
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Corus CAD (ASGES) | Age/Sex/Gene Expression Score - ASGES |
Timeline
- Start date
- 2012-04-01
- Primary completion
- 2013-03-01
- Completion
- 2013-05-01
- First posted
- 2012-03-20
- Last updated
- 2019-01-31
Locations
7 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT01557855. Inclusion in this directory is not an endorsement.