NCT01556984

Changes of Endothelial Function Before and After DSA in Patients With Diabetes

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Wuhan General Hospital of Guangzhou Military Command · Academic / Other
• Sex: All
• Age: 40 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Endothelial dysfunction is the early step of atherosclerosis. Therefore, the investigators hypothesize that digital subtraction angiography (DSA) can damage endothelial function. In this study, the investigators will select 200 diabetic patients who have a DSA for diabetic foot screening. Also, the investigators will select 100 healthy subjects as controls. The endothelial function will be determined by high resolution ultrasound before and after DSA. The investigators will observe the changes of endothelial function after DSA assay.

Conditions

• Diabetes

Interventions

Type	Name	Description
OTHER	DSA assay	All patients with diabetic foot perform a DSA assay. Before and after DSA, endothelial function will be measured.

Timeline

• Start date: 2012-10-01
• Primary completion: 2013-08-01
• Completion: 2013-10-01
• First posted: 2012-03-19
• Last updated: 2015-06-16

Locations

1 site across 1 country: China