NCT01555736

Comparison of Perennial and Preseasonal Subcutaneous Immunotherapy

A Randomised Double-blind Clinical Trial for Evaluation of Efficacy and Safety of Perennial in Comparison to Preseasonal Grass/Rye Pollen Immunotherapy in Patients Suffering From Seasonal Allergic Rhinitis

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Medical University of Lodz · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Specific immunotherapy, which involves the administration of allergic extracts to patients with symptoms of allergic disorder, is the leading therapeutical tool of modern allergology. According to the latest studies immunotherapy not only reduces symptoms' severity but also may modify the course of allergic disease by reducing the risk of new sensitisations and development of more advanced stages of the disease.It has been hypothesized basing on clinical observation that perennial immunotherapy is more effective and safer in comparison to preseasonal immunotherapy. The aim of the study was to compare the effect of perennial and preseasonal immunotherapy on rhinoconjunctivitis symptoms and safety of both treatments.

Conditions

• Seasonal Allergic Rhinitis

Interventions

Type	Name	Description
DRUG	grass (80%) and rye (20%) pollens allergoids	comparison of two schemes of immunotherapy - preseasonal and perennial immunotherapy.

Timeline

• Start date: 2003-01-01
• Primary completion: 2006-07-01
• Completion: 2006-09-01
• First posted: 2012-03-15
• Last updated: 2012-03-21

Locations

1 site across 1 country: Poland