NCT01554462

The Effects of EPA/DHA Supplementation on Cognitive Control in Children With ADHD

The Effects of Eicosapentaenoic Acid (EPA)/ Docosahexaenoic Acid (DHA) Supplementation on Cognitive Control in Children With Attention Deficit Hyperactivity Disorder (ADHD)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 79 (actual)
• Sponsor: Unilever R&D · Industry
• Sex: Male
• Age: 8 Years – 12 Years
• Healthy volunteers: Accepted

Summary

Forty children with and 40 children without Attention deficit Hyperactivity Disorder (ADHD) receive Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA) or placebo via a dietary intervention. Cognitive control functions are measured with functional Magnetic Resonance Imaging (MRI) before and after the intervention. Behavioural change is monitored with behavioural scales.

Conditions

• Attention Deficit Hyperactivity Disorder
• Healthy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Eicosapentaenoic acid / Docosahexaenoic acid	650 mg EPA + 650 mg DHA daily
DIETARY_SUPPLEMENT	Placebo dietary intervention (MUFA) in ADHD group	Placebo contains mono-unsaturated fatty acids (MUFA) in stead of poly-unsaturated fatty acids (PUFA), same energy value
DIETARY_SUPPLEMENT	Eicosapentaenoic acid / Docosahexaenoic acid	650 mg EPA and 650 mg DHA daily
DIETARY_SUPPLEMENT	Placebo dietary intervention (MUFA) in healthy control group	Placebo contains MUFA in stead of PUFA, same energy value

Timeline

• Start date: 2009-01-01
• Primary completion: 2013-01-01
• Completion: 2013-01-01
• First posted: 2012-03-15
• Last updated: 2013-12-11

Locations

1 site across 1 country: Netherlands