NCT01553903

Feasibility Study for the Determination of Oxysterols in Patients With Breast Cancer Receiving Hormonal Therapy With Tamoxifen or Not

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 29 (actual)
• Sponsor: Institut Claudius Regaud · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a biomedical study of interventional type which includes 29 patients on 9 months: 8 months recruiting and 1 month follow up. Patients with hormone dependent breast cancer metastatic or non-metastatic, for which an indication of hormonal therapy treatment (with tamoxifen or anti-aromatase) is retained, will be enrolled in this study. The main objective of this study is to evaluate the feasibility for the determination of Oxysterols (CT, CE, OCDO) in this patient population, before and after the initiation of treatment (ie, at D0 before and D28 after beginning of treatment).

Conditions

• Breast Cancer

Interventions

Type	Name	Description
DRUG	Tamoxifen,	Tamoxifen 20 mg/day during 5 years,
DRUG	Exemestane	Exemestane 25mg/day during 5 years
DRUG	Anastrozole	Anastrozole 1 mg/day during 5 years,
DRUG	Letrozole	Letrozole 2.5 mg/day during 5 years,

Timeline

• Start date: 2011-12-01
• Primary completion: 2013-05-01
• Completion: 2013-05-01
• First posted: 2012-03-14
• Last updated: 2026-04-14

Locations

1 site across 1 country: France