NCT01553006

Study of Cefditoren Pivoxil in Treatment of Childhood With Acute Rhinosinusitis

A Comparison of Cefditoren Pivoxil 10 mg/kg/Day and Cefditoren Pivoxil 20 mg/kg/Day in Treatment of Childhood With Acute Rhinosinusitis

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: Thammasat University · Academic / Other
• Sex: All
• Age: 1 Year – 15 Years
• Healthy volunteers: Accepted

Summary

Cefditoren pivoxil has been used in rhinosinusitis treatment. However, little is known about the efficacy of this drug at low and high doses.

Detailed description

The investigation was a randomized, investigator-blinded, and parallel study, conducted in patients (age 1-15 years) with acute rhinosinusitis. Two groups of patients were randomized received low (10 MKD) or high (20 MKD) of drug for 14 days. Changes in sinus symptoms scores, response rate and adverse effect were evaluated at days 7 and 14. Relapse rate was recorded at days 21 and 28. Recurrence of sinus symptoms at day 60 were assessed.

Conditions

• Rhinosinusitis

Interventions

Type	Name	Description
DRUG	cefditoren pivoxil	comparison of different dosages of cefditoren pivoxil

Timeline

• Start date: 2012-01-01
• Primary completion: 2012-08-01
• Completion: 2012-09-01
• First posted: 2012-03-13
• Last updated: 2012-03-14

Locations

1 site across 1 country: Thailand