NCT01551238

Energy Expenditure, Sleep and Macronutrients

Energy Expenditure and Sleep in Response to Protein/Carbohydrate and Fat Ratio

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Maastricht University Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine energy expenditure and sleep in response to protein/carbohydrate and fat ratio of the diet over a short-term and long-term period of time.

Detailed description

The prevalence of obesity has increased worldwide to epidemic proportions. For long-term treatment success permanent lifestyle changes are necessary with regard to approach to food, physical activity patterns and behavior to emotional stress. Moreover, an association has been shown between sleep disturbance and obesity. Weight loss strategies regarding food intake regulation mainly focused on changing patterns of fat and carbohydrate consumption during the last decades. The role of protein has largely been ignored. However, protein has been observed to increase satiety and energy expenditure to a greater extent than carbohydrate and fat and can therefore reduce energy intake. However, it still has to be confirmed if this effect is permanent or transient over a longer period of time. Moreover, dietary intakes may significantly affect sleep when macronutrient intakes are manipulated. Since sleep deprivation has been recognized as a risk factor for obesity, improving sleep by a change in macronutrient intake would be promising in the treatment of obesity.

Conditions

• Obesity
• Overweight
• Overnutrition
• Nutrition Disorders
• Body Weight
• Signs and Symptoms

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Differences in protein content of meals	Differences in protein content (energy percent) of meals
DIETARY_SUPPLEMENT	Differences in protein content of meals	Differences in protein content (energy percent) of meals

Timeline

• Start date: 2012-03-01
• Primary completion: 2013-12-01
• Completion: 2013-12-01
• First posted: 2012-03-12
• Last updated: 2013-05-03

Locations

1 site across 1 country: Netherlands