Trials / Completed
CompletedNCT01550393
Biomarkers in Urine Samples From Patients With Wilms Tumor
Discovery and Validation of Wilms Tumor Markers Using Urine Proteomics
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (estimated)
- Sponsor
- Children's Oncology Group · Network
- Sex
- All
- Age
- 120 Years
- Healthy volunteers
- Not accepted
Summary
RATIONALE: Studying samples of urine from patients with cancer in the laboratory may help doctors identify biomarkers related to cancer. PURPOSE: This clinical trial studies biomarkers in urine from patients with Wilms tumor.
Detailed description
OBJECTIVES: * To validate the prognostic performance of specific-candidate Wilms tumor markers by measuring their urinary concentration using enzyme-linked immunosorbent assays (ELISAs) in urine specimens collected at diagnosis from 50 patients with favorable histology Wilms tumor who relapsed and 50 patients who did not relapse. OUTLINE: Urine specimens are analyzed using enzyme-linked immunosorbent assays (ELISAs) for biomarkers.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | proteomic profiling | |
| OTHER | enzyme-linked immunosorbent assay | |
| OTHER | laboratory biomarker analysis | |
| OTHER | medical chart review |
Timeline
- Start date
- 2012-03-01
- Primary completion
- 2016-07-01
- First posted
- 2012-03-12
- Last updated
- 2016-07-11
Source: ClinicalTrials.gov record NCT01550393. Inclusion in this directory is not an endorsement.