NCT01549496

A Drug Interaction Study of Boceprevir in Combination With Amlodipine or Diltiazem in Healthy Volunteers

A Drug Interaction Study Investigating the Effect of Boceprevir on the Pharmacokinetics of the Calcium Channel Blockers Amlodipine and Diltiazem and Vice Versa in Healthy Volunteers

• Status: Withdrawn
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Ottawa Hospital Research Institute · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the pharmacokinetic interactions between the hepatitis C NS3 protease inhibitor boceprevir and the calcium channel blockers amlodipine and diltiazem in healthy volunteers.

Conditions

• Hepatitis C
• Hypertension

Interventions

Type	Name	Description
DRUG	Amlodipine	amlodipine 2.5 mg QD
DRUG	Diltiazem	diltiazem 120 mg qd

Timeline

• Start date: 2012-05-01
• Primary completion: 2012-09-01
• First posted: 2012-03-09
• Last updated: 2015-01-09

Locations

1 site across 1 country: Canada