NCT01545544

Observational Study of B-Cell Non Hodgkin Lymphomas (NHL) Associated With Hepatitis C Virus (HCV)

Observational Study of B-Cell Non Hodgkin Lymphomas (NHL) in Patients With Hepatitis C Virus

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 138 (actual)
• Sponsor: ANRS, Emerging Infectious Diseases · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

An prospective / retrospective multicenter observational study whose objectives are to understand the interactions between hepatitis c virus and Non Hodgkin lymphomas. The characteristics , evolution and treatment of diseases will be observed from the study.

Detailed description

Main objectives are: * Description of the clinical and histological characteristics, treatment and evolution of these NHL. * Study their physiopathology by immunological, virologic and molecular studies. The study included prospective or retrospective patients with B- Cell Non-Hodgkin lymphomas (NHL) associated with chronic hepatitis C. The patients are diagnosed or in remission of lymphoma, in relapse or failure of treatments. The enrolment period is 6 years and the total study lasts 8 years. * "Prospective patients" are followed every 6 months during one year, and all the years during 2 or 5 years. * "Retropective patients" are followed all the years during 2 or 5 years. At each follow-up, a blood sample of 50ml is withdrawn allowing ancillary studies. The enrollment is estimated at 140 patients.

Conditions

• Chronic Hepatitis C

Timeline

• Start date: 2006-11-01
• Primary completion: 2014-11-01
• Completion: 2014-11-01
• First posted: 2012-03-06
• Last updated: 2014-02-07

Locations

1 site across 1 country: France