NCT01544712

Controlled Study of Stage 3 Osteonecrosis Treatment by Bone Marrow

Treatment of Stage 3 Osteonecrosis of the Femoral Head by Autologous Transplantation of Bone Marrow Cells: a Randomized, Controlled Double Blind Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: University of Liege · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In stage 3 Osteonecrosis (ON) of the femoral head, a beneficial effect of bone marrow grafting was reported with a reduction of the functional evolution and the necessity of a total prosthesis placement in a non-controlled retrospective trial. Based on this experience, the investigators would like to start a randomized controlled double blind study on the effect of autologous implantation of autologous bone marrow cells into the necrotic lesion of stage 3 ON of the femoral head.

Conditions

• Non Traumatic Osteonecrosis of the Femoral Head (Hip)

Interventions

Type	Name	Description
PROCEDURE	core decompression with autologous bone marrow implantation	core biopsy with injection of 40 ml concentrated autologous bone marrow.
PROCEDURE	core decompression of the femoral head	core biopsy with injection of 40 ml saline solution in place of bone marrow.

Timeline

• Start date: 2004-08-01
• Primary completion: 2010-09-01
• Completion: 2010-09-01
• First posted: 2012-03-06
• Last updated: 2012-03-06

Locations

1 site across 1 country: Belgium