Clinical Trials Directory

Trials / Completed

CompletedNCT01544478

V501 Safety and Efficacy Study in Japanese Women Aged 16 to 26 Years (V501-110)

A Phase IV Open-Label, Descriptive Study to Evaluate the Safety and Effectiveness on the Incidence of HPV 6, 11, 16 and 18 Related CIN 2/3 or Worse of the Quadrivalent HPV (Types 6, 11, 16, 18) L1 Virus-Like Particle (VLP) Vaccine in 16- to 26-Year-Old Japanese Women

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
1,030 (actual)
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
Female
Age
16 Years – 26 Years
Healthy volunteers
Accepted

Summary

This study evaluated the long-term safety of quadrivalent Human Papillomavirus (HPV) types 6, 11, 16, 18 vaccine and its effectiveness in the prevention of cervical intraepithelial neoplasia (CIN), adenocarcinoma in situ, and cervical cancer related to HPV in Japanese women.

Conditions

Interventions

TypeNameDescription
BIOLOGICALV501HPV types 6, 11, 16, and 18 vaccine 0.5 mL by intramuscular injection at Day 1, Month 2, and Month 6

Timeline

Start date
2011-11-25
Primary completion
2016-08-27
Completion
2016-08-27
First posted
2012-03-06
Last updated
2018-11-28
Results posted
2017-07-07

Regulatory

Source: ClinicalTrials.gov record NCT01544478. Inclusion in this directory is not an endorsement.