Clinical Trials Directory

Trials / Terminated

TerminatedNCT01543737

Effectiveness of Two Hyaluronic Acids in Osteoarthritis of the Knee

Single-blind Randomised Pragmatic Trial Comparing the Effectiveness of Two Hyaluronic Acid Viscosupplements, DUROLANE® (Single Injection) Versus HYALGAN® (Three Injections) for Symptomatic Tibiofemoral Osteoarthritis of the Knee.

Status
Terminated
Phase
N/A
Study type
Interventional
Enrollment
290 (actual)
Sponsor
Bioventus LLC · Industry
Sex
All
Age
40 Years – 85 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to assess whether a single injection hyaluronic acid (HA) product is not inferior to a 3 injection HA product at 24 weeks (6 months), in terms of effectiveness in reducing pain when walking in patients suffering from symptomatic tibiofemoral osteoarthritis of the knee.

Detailed description

non-inferiority study of two HA products commercially availalble

Conditions

Interventions

TypeNameDescription
DEVICE3ml hyaluronic acid (DUROLANE)DUROLANE Hyaluronic acid 20mg/ml
DEVICE2ml hyaluronic acid, (HYALGAN)HYALGAN Hyaluronic acid 10mg/ml

Timeline

Start date
2012-02-01
Primary completion
2014-02-01
Completion
2014-02-01
First posted
2012-03-05
Last updated
2016-02-12

Locations

17 sites across 2 countries: France, Monaco

Source: ClinicalTrials.gov record NCT01543737. Inclusion in this directory is not an endorsement.