NCT01541059

Postoperative Analgesia Following Wisdom Teeth Removal: Ropivacaine Versus Placebo

Postoperative Analgesia in Third Molar Surgery Under General Anesthesia: Ropivacaine Versus Placebo

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Centre Hospitalier Universitaire de Nīmes · Academic / Other
• Sex: All
• Age: 16 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The main objective of this study is to demonstrate the superiority of local analgesia with ropivacaine versus placebo on postoperative pain during the first 24 hours following bilateral surgery of all four third molars under general anesthesia.

Detailed description

The secondary objectives of this study are to compare regional anesthesia by ropivacaine versus placebo for the bilateral resection of all four third molars under general anesthesia, in terms of: A. intraoperative use of propofol and remifentanil B. postoperative pain (EVN) at different time points C. in-hospital analgesic consumption D. time to first rescue analgesic request E. time spent in the post interventional treatment room F. length of hospital stay G. side effects H. analgesic consumption at home I. analgesic consumption (total) J. patient satisfaction K. Chronic pain after surgery

Conditions

• Third Molar Extraction

Interventions

Type	Name	Description
DRUG	Placebo injection	Injection of saline solution into the vestibular capsule of each tooth to be extracted.
DRUG	Ropivacaine injection	Ropivacaine is injected into the vestibular capsule of each tooth to be extracted.

Timeline

• Start date: 2012-06-01
• Primary completion: 2015-08-29
• Completion: 2015-08-29
• First posted: 2012-02-29
• Last updated: 2025-11-19

Locations

1 site across 1 country: France