NCT01540513

PET/CT Evaluation of Primary and Metastatic Brain Tumors With a Novel Radioiodinated Phospholipid Ether Analogue I-NM404

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: University of Wisconsin, Madison · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate diagnostic imaging techniques using 124I-NM404 PET/CT in human brain tumors. This goal will be accomplished by quantifying tumor uptake and determining the optimal PET/CT protocol, comparing PET tumor uptake to MRI, and calculating tumor dosimetry. The long-term goals of this research are to improve the diagnosis and treatment of malignant brain tumors by using radioiodinated NM404

Conditions

• Glioblastoma Multiforme
• Brain Metastases

Interventions

Type	Name	Description
DRUG	NM404	injection of 5.0mCi I-124 NM404 Arms: I124-NM404 brain metastases or GBM imaging Other Names: PET imaging with I-124 NM404
DRUG	NM404	injection of an experimental imaging agent, 5mCi I-124NM404

Timeline

• Start date: 2012-03-01
• Primary completion: 2014-10-01
• Completion: 2014-10-01
• First posted: 2012-02-28
• Last updated: 2019-12-02
• Results posted: 2017-12-11

Locations

1 site across 1 country: United States