NCT01539928

Dual PET/CT Imaging in Lung Cancer

Dual PET/CT Imaging in Lung Cancer (Danish Title: En og Tre Timers FDG-PET/CT Ved Lungecancer)

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 216 (estimated)
• Sponsor: Odense University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare conventional PET/CT scan performed 1 hour after injection of the radioactive tracer FDG (PET/CT\[1\]) with PET/CT performed after 3 hours (PET/CT\[3\]) in a group of patients with biopsy verified lung cancer or high suspicion of lung cancer after initial work-up (chest x-ray and CT of thorax/upper abdomen), who are potentially operable.

Detailed description

The investigators also want to: * To find the sensitivity, specificity and accuracy in PET/CT 1h and 3 h in the staging of lung cancer (N-/M-stage). Our gold standard is pathology, when not possible - follow-up (se Gold Standard 6.1.1) * To compare SUVmax with the expression of GLUT1 and G-6-Pase in tumors * To compare the expression of GLUT1 with the activity of G6Pase * To compare SUVmax, RI, tumor/liver ratio, GLUT1 and G-6-Pase with the occurrence of relapse within a year after curative surgery

Conditions

• Lung Cancer

Interventions

Type	Name	Description
OTHER	Dual FDG-PET/CT	Conventional FDG-PET/CT preformed after 1 hour and additional PET/CT 3 hours after injection

Timeline

• Start date: 2012-03-01
• Primary completion: 2014-03-01
• Completion: 2015-03-01
• First posted: 2012-02-28
• Last updated: 2013-06-25

Locations

1 site across 1 country: Denmark