NCT01537575

Intravenous Immunoglobulins for Post-Polio Syndrome

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Azienda Ospedaliera Universitaria Integrata Verona · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Postpolio syndrome is a condition that affects many polio survivors years after the acute infection and causes symptoms to increase or new symptoms to develop. Proinflammatory cytokine production within the central nervous system (CNS) indicates an underlying inflammatory process, amenable to immunomodulatory therapy. In this study the investigators sought to confirm that antiinflammatory treatment with intravenous immunoglobulin improves the disease.

Conditions

• Post-polio Syndrome

Interventions

Type	Name	Description
BIOLOGICAL	intravenous immunoglobulins	One course of Intravenous Immunoglobulins 0.4 g/kg/die for 5 consecutive days
BIOLOGICAL	Saline solution	Placebo

Timeline

• Start date: 2008-01-01
• Primary completion: 2009-12-01
• First posted: 2012-02-23
• Last updated: 2012-02-27